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How to become a Nurse Practitioner in South Carolina. Data verified 2026-03-20. Source: LicenseMap (getlicensemap.com).
Nurse Practitioner — APRN
Some information on this page has not been fully verified.
69% of data points are verified against official sources. 15 fields based on preliminary research. We recommend confirming details with your state's licensing authority. See sources below · Report incorrect data
Restricted Practice
Practice Authority
Required
Certification
Schedule III-V; Schedule II very restricted
Controlled Substances
30 hrs
CE Hours
$515
Total Fees
Non-Member
APRN Compact
Graduate Degree & Program Accreditation
VerifiedDegree Required
MSN or DNP from accredited nursing program
Program Accreditation
CCNE (Commission on Collegiate Nursing Education) or ACEN (Accreditation Commission for Education in Nursing)
Program Length
2-4 years (MSN: 2-3 years; DNP: 3-4 years)
Clinical Hours
500 hrs
Prerequisite
Active RN license; BSN preferred or required by most programs
Specialty Tracks
Nurse practitioners must earn a Master of Science in Nursing (MSN) or Doctor of Nursing Practice (DNP) degree from a CCNE or ACEN accredited program. Programs typically include 500-1,000+ supervised clinical hours and prepare NPs for national certification in their chosen specialty.
Certification Requirements
VerifiedNational Certification Required
AANP or ANCC Board Certification
Certification Body
AANP (American Academy of Nurse Practitioners) or ANCC (American Nurses Credentialing Center)
Certification Exam
AANP Certification Examination or ANCC NP Board Certification Examination in chosen specialty
Certification Fee
$315
Specialty Certification
National board certification in population-focus area required (e.g., FNP, AGPCNP, PMHNP)
Most states require nurse practitioners to hold national board certification from the AANP (American Association of Nurse Practitioners) or ANCC (American Nurses Credentialing Center). Certification exams are specialty-specific and must align with the NP's graduate education.
Practice Authority Level & Independence
Mostly verifiedRestricted Practice
Practice Authority Level
Independent Practice
No
Collaborative Agreement
Required
Supervision Details
Physician supervision/delegation required in South Carolina
Practice authority levels vary by state: Full Practice Authority (FPA) allows NPs to evaluate, diagnose, and prescribe independently. Reduced Practice Authority requires a collaborative agreement. Restricted Practice Authority requires physician supervision. Some states offer a transition period before granting full independence.
Prescribing & Controlled Substances
Mostly verifiedPrescriptive Authority
Granted
Controlled Substances
Schedule III-V; Schedule II very restricted
DEA Registration
Required
Collaborative Agreement Required for Prescribing
State Controlled Substance Registration
South Carolina requires state controlled substance registration for prescribing scheduled medications
Prescriptive authority varies by state and practice authority level. Full Practice Authority states generally allow NPs to prescribe independently, including controlled substances. Reduced and restricted states may require collaborative agreements or physician oversight for prescribing. DEA registration is required for controlled substance prescribing.
| Fee | Amount |
|---|---|
Application Fee | $100 |
Certification Exam Fee AANP or ANCC certification exam fee; varies by membership status | $315 |
License Fee | $100 |
DEA Fee DEA registration for 3 years; required for prescribing controlled substances | $888 |
Collaborative Agreement Fee Not a government fee | Varies; typically $500-$5,000/year paid to collaborating physician. Not a state fee — negotiated privately. |
Renewal Fee | $80 |
Total Initial Fees Includes application ($100), certification exam ($315), and license ($100) fees (excludes DEA which is a separate federal fee) | $515 |
Renewal & Continuing Education
Mostly verified2 years
Renewal Period
30 hrs
CE Hours Required
$80
Renewal Fee
Pharmacology CE Requirement
15 pharmacology CE within 30 total
Practice Hour Requirements
Most states require documentation of active NP practice; specific hour requirements vary
Regulatory Board
NP licenses must be renewed on schedule with the state board of nursing. Most states require continuing education hours, often with specific pharmacology CE requirements. Many states also require proof of active practice hours and maintenance of national board certification.
Out-of-State Reciprocity
Mostly verifiedAccepts Out-of-State Credentials
APRN Compact
Non-Member
Endorsement Available
Yes
Reciprocity Requirements
The APRN Compact allows nurse practitioners to practice across state lines in member states. For non-compact states, NPs must apply for licensure by endorsement, which typically requires national certification, verification of credentials, and meeting state-specific requirements including practice authority regulations.
South Carolina requires a written practice agreement with a physician. Schedule II prescribing is limited to a specific formulary. Physician must review 20% of medical records.
South Carolina requires graduation from an accredited MSN or DNP program and national board certification for NP licensure.
Practice authority: Restricted Practice Authority - physician supervision required.
NPs may prescribe Schedule II-V (practice agreement required).
30 continuing education hours required per 2-year renewal cycle.
10 hours pharmacology CE required.
APRN Compact not yet active as of March 2026. Requires 7 states to enact; fewer than 7 have done so.
APRN Compact not yet active as of March 2026. Requires 7 states to enact; fewer than 7 have done so.
Explore requirements for other professional licenses in South Carolina.
How this state compares to 50 others for this profession
Timeline
#1 of 51
Salary
#46 of 51
Cost
#22 of 51
Processing
#1 of 51
Based on May 2024 Bureau of Labor Statistics OEWS data for Nurse Practitioners (SOC 29-1171)
Entry Level
$103,000
25th percentile
Median
$116,240
-10% vs. national avg ($129,210)Experienced
$130,010
75th percentile
Wage Distribution (Annual)
5,850 employed in this state
Source: BLS OEWS – Nurse Practitioners (May 2024)
National employment projections for 2024-2034
Projected Growth
+26%
Very High DemandNew Jobs
+84,200
over 10 years
Annual Openings
29,200
per year (avg.)
323,600 currently employed nationwide (2024)
Source: BLS Employment Projections 2024-2034 (September 2025)
Nursing Career Ladder+220% salary growth potential
You are here
Nurse Practitioner
$116,240
MSN or DNP + national certification
State-approved training program (4-12 weeks)
$36,370
Practical nursing program (12-18 months) + NCLEX-PN
$59,050
ADN or BSN degree + NCLEX-RN
$79,900
You are here
Nurse Practitioner
MSN or DNP + national certification
$116,240
Salary data from BLS OEWS May 2024 for this state. Career paths represent common advancement routes — actual progression may vary. Bureau of Labor Statistics — Occupational Outlook Handbook
Government fees and exam costs to obtain your initial license
Note: These are government licensing fees only. Education/training program costs (tuition, books, etc.) are not included as they vary widely by institution.
Estimated total: 112–234 weeks
Timeline estimated from licensing requirements on this page.
Source: South Carolina Board of Nursing — Licensing Requirements
4–12 weeks
Estimated processing time
Source: South Carolina Board of Nursing — Licensing Requirements
Study guides for the AANP and ANCC certification exams.
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Accessed 2026-03-20
Updated January 2026
Accessed 2026-03-20
Accessed 2026-03-20
South Carolina grants Restricted Practice practice authority to nurse practitioners. South Carolina requires a collaborative agreement for NP practice. All licensing is managed through the South Carolina Board of Nursing.
Requirements vary by state. Always verify current requirements with your state licensing authority.